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1

First 2-Hydroxy-3-Methylbut-3-Enyl Substituted Xanthones Isolated From Plants: Structure Elucidation, Synthesis and Antifungal Activity

Oger, Jean-Michel, Morel, CÉcile, Helesbeux, Jean-Jacques, Litaudon, Marc, Séraphin, Denis, Dartiguelongue, Caroline, Larcher, Gérald, Richomme, Pascal, Duval, Olivier

Journal:

Natural Product Research

Year:

2003

Language:

english

File:

PDF, 126 KB

english, 2003

2

ChemInform Abstract: ortho-Prenylphenol Photooxygenation as a Straightforward Access to ortho-(2-Hydroxy-3-methylbut-3-enyl)phenols.

Jean-Jacques Helesbeux, David Guilet, Denis Seraphin, Olivier Duval, Pascal Richomme, Jean Bruneton

Journal:

Year:

2000

File:

PDF, 30 KB

2000

3

Regioselectivity in the Ene Reaction of Singlet Oxygen with ortho-Prenylphenol Derivatives.

Jean-Jacques Helesbeux, Olivier Duval, David Guilet, Denis Seraphin, David Rondeau, Pascal Richomme

Journal:

Year:

2003

File:

PDF, 161 KB

2003

4

ChemInform Abstract: 2H-Pyran-2-one-3-carbothioamide Derivatives: Synthesis and Reaction with Hydrazine Hydrate.

Malika Makhloufi-Chebli, Maamar Hamdi, Artur M. S. Silva, Olivier Duval, Jean-Jacques Helesbeux

Journal:

Year:

2009

File:

PDF, 22 KB

2009

5

Novel polydentate phosphonic acids: Protonation and stability constants of complexes with Fe(III) and Cu(II) in aqueous medium

Nabila Aliouane, Salah Chafaa, Tahar Douadi, Jean-Jacques Hélesbeux, Mustayeen A. Khan, Olivier Duval, Gilles Bouet

Journal:

Heteroatom Chemistry

Year:

2010

Language:

english

File:

PDF, 256 KB

english, 2010

6

2H-Pyran-2-one-3-carbothioamide derivatives: Synthesis and reaction with hydrazine hydrate

Malika Makhloufi-Chebli, Maamar Hamdi, Artur M. S. Silva, Olivier Duval, Jean-Jacques Helesbeux

Journal:

Journal of Heterocyclic Chemistry

Year:

2009

Language:

english

File:

PDF, 103 KB

english, 2009

7

Free and immobilized matrix molecules: impairing ionization by quenching secondary ion formation in laser desorption MS

Andreas Schinkovitz, Ghislain Tsague Kenfack, Eric Levillain, Marylène Dias, Jean-Jacques Helesbeux, Séverine Derbré, Denis Séraphin, Pascal Richomme

Journal:

Journal of Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 265 KB

english, 2011

8

Synthesis of the trans-fusarinine scaffold

Samuel Bertrand, Olivier Duval, Jean-Jacques Hélesbeux, Gérald Larcher, Pascal Richomme

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 527 KB

english, 2010

9

ortho-Prenylphenol photooxygenation as a straightforward access to ortho-(2-hydroxy-3-methylbut-3-enyl)phenols

Jean-Jacques Helesbeux, David Guilet, Denis Séraphin, Olivier Duval, Pascal Richomme, Jean Bruneton

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

10

The anti-invasive activity of synthetic alkaloid ethoxyfagaronine on L1210 leukemia cells is mediated by down-regulation of plasminogen activators and MT1-MMP expression and activity

Jérôme Devy, Farid Ouchani, Christelle Oudot, Jean Jacques Helesbeux, Enguerran Vanquelef, Stéphanie Salesse, Fanja Rabenoelina, Siana Al-Khara, Isabelle Letinois, Olivier Duval, Laurent Martiny, Emma

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 725 KB

english, 2011

11

Crystal Structure of Ethoxidine, A Synthetic Quaternary Benzo[c]phenanthridine

Jean-Jacques Helesbeux, Enguerran Vanquelef, Jean Guillon, Jean-Michel Léger, Olivier Duval

Journal:

Journal of Chemical Crystallography

Year:

2011

Language:

english

File:

PDF, 1.68 MB

english, 2011

12

Synthesis of 2-hydroxy-3-methylbut-3-enyl substituted coumarins and xanthones as natural products. Application of the Schenck ene reaction of singlet oxygen with ortho-prenylphenol precursors

Jean-Jacques Helesbeux, Olivier Duval, Caroline Dartiguelongue, Denis Séraphin, Jean-Michel Oger, Pascal Richomme

Journal:

Year:

2004

Language:

english

File:

PDF, 254 KB

english, 2004

13

Regioselectivity in the ene reaction of singlet oxygen with ortho-prenylphenol derivatives

Jean-Jacques Helesbeux, Olivier Duval, David Guilet, Denis Séraphin, David Rondeau, Pascal Richomme

Journal:

Year:

2003

Language:

english

File:

PDF, 337 KB

english, 2003

14

Studies on the reactivity of a tertiary allylic alcohol in an acetophenonic series, a model for natural products synthesis

J. J. Hélesbeux, D. Séraphin, O. Duval, P. Richomme, J. Bruneton

Journal:

Journal of Pharmacy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

15

ChemInform Abstract: ortho-Lithium/Magnesium Carboxylate-Driven Aromatic Nucleophilic Substitution Reactions on Unprotected Naphthoic Acids.

Regadia Aissaoui, Arnaud Nourry, Ariane Coquel, Thi Thanh Ha Dao, Aicha Derdour, Jean-Jacques Helesbeux, Olivier Duval, Anne-Sophie Castanet, Jacques Mortier

Journal:

Year:

2012

File:

PDF, 34 KB

2012

16

Synthesis, crystal structure, and characterization of thiophene-3-carboxaldoxime complexes with cobalt(II), nickel(II) and copper(II) halides

Kusaï Alomar, Jean-Jacques Hélesbeux, Magali Allain, Gilles Bouet

Journal:

Journal of Molecular Structure

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

17

Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii

Anne-Emmanuelle Hay, Jean-Jacques Hélesbeux, Olivier Duval, Medhi Labaïed, Philippe Grellier, Pascal Richomme

Journal:

Year:

2004

Language:

english

File:

PDF, 275 KB

english, 2004

18

Novel Cytotoxic 4-Phenylfuranocoumarins from Calophyllum d ispar

Guilet, David, Hélesbeux, Jean-Jacques, Séraphin, Denis, Sévenet, Thierry, Richomme, Pascal, Bruneton, Jean

Journal:

Journal of Natural Products

Year:

2001

Language:

english

File:

PDF, 73 KB

english, 2001

19

Antimicrobial Lexitropsins Containing Amide, Amidine, and Alkene Linking Groups

Anthony, Nahoum G., Breen, David, Clarke, Joanna, Donoghue, Gavin, Drummond, Allan J., Ellis, Elizabeth M., Gemmell, Curtis G., Helesbeux, Jean-Jacques, Hunter, Iain S., Khalaf, Abedawn I., Mackay, Si

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 316 KB

english, 2007

20

Anti-AGEs and antiparasitic activity of an original prenylated isoflavonoid and flavanones isolated from Derris ferruginea

Morel, Sylvie, Helesbeux, Jean-Jacques, Séraphin, Denis, Derbré, Séverine, Gatto, Julia, Aumond, Marie-Christine, Abatuci, Yannick, Grellier, Philippe, Beniddir, Mehdi A., Le Pape, Patrice, Pagniez, F

Journal:

Phytochemistry Letters

Year:

2013

Language:

english

File:

PDF, 351 KB

english, 2013

21

ortho -Lithium/Magnesium Carboxylate-Driven Aromatic Nucleophilic Substitution Reactions on Unprotected Naphthoic Acids

Aissaoui, Regadia, Nourry, Arnaud, Coquel, Ariane, Dao, Thi Thanh Hà, Derdour, Aicha, Helesbeux, Jean-Jacques, Duval, Olivier, Castanet, Anne-Sophie, Mortier, Jacques

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 511 KB

english, 2012

22

Maladie veineuse chronique au travail

Tarsissi, O., Gausseres, V., Raffray, M., Helesbeux, S.

Journal:

Archives des Maladies Professionnelles et de l'Environnement

Year:

2005

File:

PDF, 87 KB

2005

23

Synthesis and PC3 androgen-independent prostate cells antiproliferative effect of fagaronine derivatives

Vanquelef, Enguerran, Hélesbeux, Jean-Jacques, Duval, Olivier, Debiton, Eric, Barthomeuf, Chantal, Jarry, Christian, Forfar, Isabelle, Richomme, Pascal

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 213 KB

english, 2007

24

Synthesis and Antimalarial Activity of Some New 1,2-Dioxolane Derivatives

Helesbeux, Jean-Jacques, Peyronnet, Damien, Labaïed, Mehdi, Grellier, Philippe, Frappier, François, Seraphin, Denis, Richomme, Pascal, Duval, Olivier

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 267 KB

english, 2002

25

Ethoxyfagaronine, a synthetic analogue of fagaronine that inhibits vascular endothelial growth factor-1, as a new anti-angiogeneic agent

Ouchani, Farid, Jeanne, Albin, Thevenard, Jessica, Helesbeux, Jean-Jacques, Wahart, Amandine, Letinois, Isabelle, Duval, Olivier, Martiny, Laurent, Charpentier, Emmanuelle, Devy, Jérôme

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 8.83 MB

english, 2015

26

Synthesis of New Benzylic Di-, Tri-, and Tetraphosphonic Acids as Potential Chelating Agents

Aliouane, Nabila, Hélesbeux, Jean-Jacques, Douadi, Tahar, Khan, Mustayeen A., Bouet, Gilles, Chafaa, Salah, Duval, Olivier

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

2011

Language:

english

File:

PDF, 269 KB

english, 2011

27

Synthesis and Cytotoxic Activity Against a Non-small-cell Bronchopulmonary Carcinoma Line (NSCLC-N6) of Benzofuran Enantiomeric Derivatives

Hélesbeux, J.J., Duval, O., Séraphin, D., Roussakis, C., Richomme, P.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 423 KB

english, 2003

28

Influence of fungal exudates of Alternaria dauci on carrot partial resistance

Lecomte, M., Hamama, L., Voisine, L., Gatto, J., Hélesbeux, J.-J., Séraphin, D., Peña-Rodriguez, L.M., Richomme, P., Boedo, C., Yovanopoulos, C., Gyomlai, M., Briard, M., Simoneau, P., Poupard, P., Be

Journal:

Acta Horticulturae

Year:

2017

Language:

english

File:

PDF, 419 KB

english, 2017

29

Efficient ortho -formylation in vitamin E series, application to the semi-synthesis of natural 5- and 7-formyl-δ-tocotrienols revealing an unprecedented 5-bromo-7-formyl exchange

Alsabil, Khaled, Viault, Guillaume, Suor-Cherer, Sorphon, Helesbeux, Jean-Jacques, Merza, Joumaa, Dumontet, Vincent, Peña-Rodriguez, Luis Manuel, Richomme, Pascal, Séraphin, Denis

Journal:

Year:

2017

Language:

english

File:

PDF, 659 KB

english, 2017

30

Concise semisynthesis of novel phenazine-vitamin E hybrids via regioselective tocopheryl ortho -quinone formation

Viault, Guillaume, Helesbeux, Jean-Jacques, Richomme, Pascal, Séraphin, Denis

Journal:

Tetrahedron Letters

Year:

2018

Language:

english

File:

PDF, 787 KB

english, 2018

31

Targeting Focal Adhesion Assembly by Ethoxyfagaronine Prevents Lymphoblastic Cell Adhesion to Fibronectin

Ouchani, F., Devy, J., Rusciani, A., Helesbeux, J. J., Salesse, S., Letinois, I., Gras-Billart, D., Duca, L., Duval, O., Martiny, L., Charpentier, E.

Journal:

Analytical Cellular Pathology

Year:

2012

Language:

english

File:

PDF, 2.54 MB

english, 2012

32

Triazolobithiophene Light Absorbing Self-Assembled Monolayers: Synthesis and Mass Spectrometry Applications

Kenfack, Ghislain Tsague, Schinkovitz, Andreas, Babu, Suresh, Elouarzaki, Kamal, Dias, Marylène, Derbré, Séverine, Helesbeux, Jean-Jacques, Levillain, Eric, Richomme, Pascal, Séraphin, Denis

Journal:

Year:

2011

Language:

english

File:

PDF, 311 KB

english, 2011

33

“The 24th Conference” of the Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A)

Hélesbeux, Jean-Jacques, Duval, Olivier

Journal:

Pharmaceuticals

Year:

2017

Language:

english

File:

PDF, 6.10 MB

english, 2017

34

Aldaulactone – An Original Phytotoxic Secondary Metabolite Involved in the Aggressiveness of Alternaria dauci on Carrot

Courtial, Julia, Hamama, Latifa, Helesbeux, Jean-Jacques, Lecomte, Mickaël, Renaux, Yann, Guichard, Esteban, Voisine, Linda, Yovanopoulos, Claire, Hamon, Bruno, Ogé, Laurent, Richomme, Pascal, Briard,

Journal:

Frontiers in Plant Science

Year:

2018

Language:

english

File:

PDF, 2.03 MB

english, 2018

35

Pro-Angiogenic Effects of Low Dose Ethoxidine in a Murine Model of Ischemic Hindlimb: Correlation between Ethoxidine Levels and Increased Activation of the Nitric Oxide Pathway

Clere, Nicolas, To, Kim Hung Thien, Legeay, Samuel, Bertrand, Samuel, Helesbeux, Jean Jacques, Duval, Olivier, Faure, Sébastien

Journal:

Year:

2017

Language:

english

File:

PDF, 2.42 MB

english, 2017

36

Efficient Semi-Synthesis of Natural δ-( R )-Tocotrienols from a Renewable Vegetal Source

Ville, Alexia, Viault, Guillaume, Hélesbeux, Jean-Jacques, Guilet, David, Richomme, Pascal, Séraphin, Denis

Journal:

Journal of Natural Products

Year:

2019

File:

PDF, 989 KB

2019

37

Novel Insights into the Mode of Action of Vasorelaxant Synthetic Polyoxygenated Chalcones

Legeay, Samuel, TrÃ¢n, Kien, Abatuci, Yannick, Faure, SÃ©bastien, Helesbeux, Jean-Jacques

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 883 KB

2020

38

Structure-based design, semi-synthesis and anti-inflammatory activity of tocotrienolic amides as 5-lipoxygenase inhibitors

Dinh, Chau Phi, Ville, Alexia, Neukirch, Konstantin, Viault, Guillaume, Temml, Veronika, Koeberle, Andreas, Werz, Oliver, Schuster, Daniela, Stuppner, Hermann, Richomme, Pascal, Helesbeux, Jean-Jacque

Journal:

European Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.48 MB

2020

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